2015;2015:472593. doi: 10.1155/2015/472593. 2013;13:44. doi: 10.1673/031.013.4401. Current pharmacological and phytochemical studies of the plant Alpinia galanga. Ginger with diclofenac resulted in a greater improvement in WOMAC and VAS scores than the individual treatments. There is evidence of its specific effect on the MexAB-OprM and AcrAB-TolC efflux pumps, present in P. aeruginosa and Enterobacter aerogenes, respectively. There was no clear evidence to suggest that ginger extract was superior to a placebo or active control in reducing joint pain or improving function. An ethanolic extract of the bark of Alstonia scholaris enhanced the anticancer activity of berberine in Ehrlich ascites carcinoma-bearing mice. By continuing you agree to the use of cookies. Liu J, Fernandez D, Gao Y, Pierre S, Gao Y, Dai G. Insects. Coriandrum sativum was shown to act protectively against the deleterious effects of disturbance of the lipid metabolism in experimental colon cancer in rats (Chithra and Leelamma, 2000) (Fig. The . Results showed that Alpinia galanga rhizome extract gives better anthelmintic activity at all the tested doses. View abstract. galangal ex tract was 0.325 mg/ml and the . Rhizome extract of Alpinia galanga have high phenolic and flavonoid contents when compared to leaf extract. Phenylalanine arginine β-naphthylamide (PAβN) is an effective inhibitor of bacterial efflux pump systems. Annona squamosa (Annonaceae) extract decreased the expression of cluster of differentiation 40 (CD40) and NF-kB1. Phytochemicals present in herbal extracts can inhibit or disrupt the activities of MDR bacteria by influencing the activities of efflux pumps, β lactamase enzymes, resistance plasmids, and bacterial gene transposition. The activity of the hexane extract against detoxification enzymes, carboxylesterase (CE) and glutathione transferase (GST) also was determined in vitro. Although C. domestica also known as C. longa, has not traditionally been used for anti-carcinogenic purposes, recent investigations show that this plant has promising effects in this area, mainly to be ascribed to curcumin (Gupta et al., 2012). A significant reduction in pain and disability was in favor of ginger. 2020 May;23(5):465-475. doi: 10.1089/jmf.2019.4490. Antileishmanial phenylpropanoids from Alpinia galanga (Linn.) Although the mechanism is not fully understood, this compound inhibits activation of NF-κB and NF-κB-regulated gene expression. 41 Fig. These activities are largely attributed to the sesquiterpene compound xanthorrhizol isolated from this plant which was observed to significantly increase apoptosis in HeLa cells (Ismail et al., 2005). The extracts of plants such as Psoralea corylifolia (Fabaceae) and Centella asiatica (Apiaceae) block the keratinocyte replication (IC50 values of 18.4 ± 0.6 and 209.9 ± 9.8 mg/mL, respectively), while the antipsoriasis activities of the plant Centella asiatica are suggested due to the existence of triterpenoid glycosides madecassoside and asiaticoside compounds (IC50 values of 8.6 ± 0.1 and 8.4 ± 0.6 μM respectively) in the extracts.39,40, Alpinia galanga (Zingiberaceae), Curcuma longa, and Annona squamosa have been evaluated for antipsoriasis activity using the HaCaT keratinocyte cell line, and it was found out that each of the selected plants has a specific influence on psoriasis activity. The consumption of Ardisia compressa tea (aqueous extract) resulted in complete inhibition of the chemically induced hepatocarcinogenesis in Wistar rats (De Mejia and Ramirez, 2004). Panduratin, a chalcone derivative isolated from Kaemferia pandurata, also a member of the Zingiberaceae family rhizoma has been reported to suppress carcinogenesis in human colon cancer cell lines (Kirana et al., 2003; Yun et al., 2005). CONCLUSIONS: We concluded that the extract of Alpinia galanga exerts pro-apoptotic effects in a breast cancer-derived cell line and could be considered as a potential chemotherapeutic agent in breast cancer. Rhizomes of Alpinia galanga were extracted with hexane, dichloromethane, ethyl acetate and methanol, respectively. COVID-19 is an emerging, rapidly evolving situation. The extract exhibited significant anthelmintic activity at a concentration of 100mg/ml in this case it was found that aqueous extract gives better activity compared to the standard. Puangsomchit A, Bullangpoti V, Pluempanupat W. Commun Agric Appl Biol Sci. However, we evaluated four extracts of Alpinia galanga Wild Linn (Zingiberaceae) rhizomes against adult flies and found hexane and ethanol extracts to be most effective (LC50 = 4,866 and 6,337 ppm, respectively, after 24 h). Boil and filter it. strong inhibitory effec t against S. aureus. Alpinia galanga plant is used in medicine and in food preparation. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/B9780444537171016590, URL: https://www.sciencedirect.com/science/article/pii/B9780128110799000136, URL: https://www.sciencedirect.com/science/article/pii/B9780128138205000064, URL: https://www.sciencedirect.com/science/article/pii/B9780123985392000124, URL: https://www.sciencedirect.com/science/article/pii/S0378874116304779, URL: https://www.sciencedirect.com/science/article/pii/S2210803314000049, Meyler's Side Effects of Drugs (Sixteenth Edition), A. Parsaeimehr, ... R. Parra-Saldívar, in, The Microbiology of Skin, Soft Tissue, Bone and Joint Infections, Nutrients and Dietary Supplements for Osteoarthritis, Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases (Second Edition), Perspectives and Key Factors Affecting the Use of Herbal Extracts against Multidrug-Resistant Gram-Negative Bacteria, Ali Parsaeimehr, ... Amir Reza Jassbi, in, Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components, Plants used to treat diabetes in Sri Lankan Siddha Medicine – An ethnopharmacological review of historical and modern sources, Saravanan V. Sathasivampillai, ... Michael Heinrich, in, Jamu: Indonesian traditional herbal medicine towards rational phytopharmacological use, Chattopadhyay et al., 2004a,b; Karunagaran et al., 2005, Okazaki et al., 2005; Kirana et al., 2003, Agarwal et al., 2003; Sharma et al., 2005, Kirana et al., 2003; Manju and Nalini, 2005. NCI CPTC Antibody Characterization Program. Thus, A. galanga extract, which has trans-cinnamic acid as an active ingredient, can control the larvae of all three essential mosquito species. Located in the thriving city, Shaanxi, China, Summit Ingredients now brings you competitive price alpinia leaf extract powder 5:1, lesser galangal rhizome extract, alpinia officinarum hance made of pure natural materials from its professional factory. Plants from the family Zingiberaceae are the most frequently used ingredient of jamu. Spodoptera exigua Hübner is one of the most important agricultural pests in Thailand. The literature shows the antimicrobial activities of herbal extracts can range from 100 to 1000 μg/mL (using the MIC test). For instance, Curcuma longa extract reduced the expression of colony stimulating factor 1 (CSF-1), interleukin 8 (IL-8), nuclear factor NF-kappa-B p100 subunit (NF-kB2), nuclear factor NF-kappa-B p105 subunit (NF-kB1) and nuclear factor NF-kappa-B p65 subunit (RelA). The combination of anticancer drugs such as paclitaxel with herbal extracts e.g. National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Research shows that galangal extract exerts an antimicrobial effect on several bacteria known for infecting foods, including staphylococcus, E. coli, listeria, salmonella and clostridium. Kaushik D, Yadav J, Kaushik P, Sacher D, Rani R. Zhong Xi Yi Jie He Xue Bao. Since the discovery of multidrug resistance in bacteria, the efficacy of some common antimicrobials is unfortunately falling, but herbal medicines can offer some alternatives. However, the toxicity is less than synthetic pesticide like Temephos. Galangal is fro… Two compounds, (E)-p-acetoxycinnamyl alcohol and (E)-p-coumaryl alcohol ethyl ether, were identified as active ingredients and found to be more active than total hexane extract (LC50 = 3,654 and 4,044 ppm, respectively, after 24 h). Fankam and colleagues reported that Dichrostachys glomerata extracts had synergy with chloramphenicol, norfloxacin, and tetracycline and significantly increased the activity of PAβN as an efflux pump inhibitor (69.2% with an MIC of ≤ 1024 μg/mL) [63]. Galangal belongs to the ginger family. Eleven Curcuma species (Curcuma aeruginosa, C. aurantiaca, C. colorata, C. domestica (synonym: C. longa), C. euchroma, C. mangga, C. petiolata, C. purpurascens, C. soloensis, C. xanthorrhizae, and C. zedoria) have been used traditionally as a spice and to treat several illnesses such as appendicitis, asthma, itch, rheumatism, abdominalgia, anaemia, hypertension, diarrhoea, and dysentery (Hatcher et al., 2008). 53, Yuan Z. Lim, ... Yuanyuan Wang, in Bioactive Food as Dietary Interventions for Arthritis and Related Inflammatory Diseases (Second Edition), 2019, Ginger may have antiinflammatory effects by inhibiting COX and lipoxygenase. Impact of Alpinia galanga rhizome extract on Bactrocera dorsalis population. Galangal ROOT TINCTURE. After that boil until reaching wax state and mix Pandanus odorifer flower, Crocus sativus stigma, Cinnamomum cappara-coronde resin, dried cow gallstone and male deer musk together. 1:2 100 ml $29.00 CAD. It does not reveal its actual effects and skin compatibility. 2015. Anti-tumor and anti-dementia effects have been observed in rodents. Copyright © 2020 Elsevier B.V. or its licensors or contributors. The studies reviewed suggest that curcumin has potential in the prevention and therapy of cancer (Agarwal et al., 2003; Sharma et al., 2005). In this regard, 5-hydroxy-2-methyl-1,4-naphthaquinone (plumbagin), derived from the root of Plumbago zeylanica, has shown an inhibitory influence on R-plasmids from resistant E. coli. In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. [1]. This item: Galangal Root Alcohol-Free Liquid Extract, Organic Organic Galangal (Alpinia Galangal) Dried Root… $24.95 ($12.48 / 1 Fl Oz) In Stock. 1). Galangal juice can be applied topically for the treatment of many skin diseases. Preclinical and clinical studies with curcumin in relation to its anticarcinogenic potential have been reviewed. Andrographis paniculata also called sambiloto by native Indonesians has been intensively investigated for its anticarcinogenic activity. Alpinia species show promise as anti-fungals, hypotensives, enhancers of sperm count and motility. It is a basic spice in the Indonesian national dish “nasi goreng,” a rice dish cooked with vegetables, meat, gravy, fruit, and mushrooms. Galangal rhizomes appear on the market as branched or simple rhizome fragments with wavy, reddish-brown annulations of the leaf bases that have an aromatic, spicy, and pungent odor and flavor. Pharm Biol 2018;56(1):294-301. The roots of Alpinia galanga and Alpinia officinarum are well identified in trade as greater and lesser galangal respectively. Curcumin is the main phenolic constituent of the genus especially in the rhizoma of tumeric (C. domestica). An effective inhibitor of bacterial efflux pump systems accordingly, the most frequently used ingredient of jamu plant is as... 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